Alexander J Lepak Selected Research

APX001A

1/2019	APX001 Pharmacokinetic/Pharmacodynamic Target Determination against Aspergillus fumigatus in an In Vivo Model of Invasive Pulmonary Aspergillosis.
1/2018	In Vivo Pharmacokinetics and Pharmacodynamics of APX001 against Candida spp. in a Neutropenic Disseminated Candidiasis Mouse Model.

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Alexander J Lepak Research Topics

Disease

18	Infections 10/2020 - 12/2011
8	Body Weight (Weight, Body) 10/2020 - 01/2013
7	Pneumonia (Pneumonitis) 12/2021 - 11/2012
5	Bacterial Pneumonia 01/2020 - 01/2016
4	Invasive Candidiasis 11/2019 - 02/2015
4	Candidiasis (Moniliasis) 11/2019 - 11/2013
4	Invasive Pulmonary Aspergillosis 01/2019 - 01/2013
3	Communicable Diseases (Infectious Diseases) 12/2021 - 11/2014
2	COVID-19 10/2021 - 01/2021
2	Respiratory Tract Infections (Respiratory Tract Infection) 06/2016 - 01/2016
1	Soft Tissue Infections 12/2021
1	Urinary Tract Infections (Urinary Tract Infection) 12/2021
1	Invasive Fungal Infections 10/2020
1	Bacterial Infections (Bacterial Infection) 06/2016
1	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 06/2016
1	Sepsis (Septicemia) 06/2016
1	Drug-Related Side Effects and Adverse Reactions 11/2014
1	Staphylococcal Pneumonia 11/2012

Drug/Important Bio-Agent (IBA)

9	Anti-Bacterial Agents (Antibiotics)IBA 12/2021 - 06/2016
6	Pharmaceutical PreparationsIBA 10/2020 - 11/2013
4	ProdrugsIBA 01/2019 - 11/2013
3	isavuconazoleIBA 10/2020 - 11/2013
3	omadacyclineIBA 01/2020 - 01/2017
3	RezafunginIBA 11/2019 - 01/2018
2	ProcalcitoninIBA 01/2021 - 06/2016
2	delafloxacinIBA 10/2019 - 01/2016
2	FluoroquinolonesIBA 10/2019 - 01/2016
2	Antifungal AgentsIBA 01/2019 - 12/2011
2	APX001AIBA 01/2019 - 01/2018
2	EchinocandinsIBA 01/2018 - 11/2013
2	TriazolesIBA 11/2013 - 11/2013
1	Polymyxins (Polymyxin)IBA 10/2020
1	Therapeutic UsesIBA 01/2020
1	cefepime-zidebactamIBA 10/2019
1	kbp-7072IBA 01/2019
1	Fosfomycin FDA Link 01/2017
1	TetracyclinesIBA 01/2017
1	eravacyclineIBA 01/2017
1	7- dimethylamino- 9- (2,2- dimethylpropyl)aminomethylcyclineIBA 01/2017
1	Vancomycin FDA LinkGeneric 01/2017
1	telavancin FDA Link 01/2017
1	Dihydrotachysterol (AT 10)IBA 10/2015
1	Methicillin (Metin)FDA Link 10/2015
1	enfumafunginIBA 02/2015
1	Bacteriocins (Lantibiotics)IBA 02/2015
1	ibrexafungerpIBA 02/2015
1	microbisporicinIBA 02/2015
1	glucan synthaseIBA 02/2015
1	Anti-Infective Agents (Microbicides)IBA 11/2014
1	Micafungin (FK463)FDA Link 11/2013
1	posaconazole FDA Link 01/2013
1	tedizolid phosphateIBA 11/2012
1	Linezolid (Zyvox)FDA Link 11/2012
1	Oxazolidinones (2 Oxazolidone)IBA 11/2012

Therapy/Procedure

3	Therapeutics 01/2020 - 11/2013
2	Duration of Therapy 01/2019 - 11/2014
2	Oral Administration 01/2018 - 10/2015
1	Intravenous Administration 01/2018
1	Transplantation 12/2013